Analysis of chromosome detection results in 1 237 infertile patients
10.3969/j.issn.1673-4130.2016.17.021
- VernacularTitle:1237例不孕症患者染色体检查结果分析
- Author:
Jing ZHAO
;
Xiang HUANG
;
Yanfang ZHANG
;
Shaoxia LIANG
;
Guobing ZHENG
- Publication Type:Journal Article
- Keywords:
infertility;
karyotype;
chromosome abnormality
- From:
International Journal of Laboratory Medicine
2016;37(17):2411-2412,2415
- CountryChina
- Language:Chinese
-
Abstract:
Objective To perform the chromosome detection in 1 237 infertile patients for analyzing the karyotypes results and investigating the relationship between infertility and chromosome abnormalities .Methods The peripheral venous blood samples in 1 237 infertile patients in our hospital from March 2010 to December 2014 were collected ,performed the lymphocyte culture ,ob‐tained cells ,fixed under hypotonic condition ,prepared the section and observed them by microscope after G‐banding treatment .Re‐sults Among 1 237 patients ,111 cases abnormal karyotypes were detected with the total abnormal detection rate of 8 .9% ,in which ,57 cases were sex chromosomes abnormality ,54 cases were euchromosomes abnormality .Conclusion Chromosome abnor‐mality is one of the important causes leading to primary infertility .Infertility caused by chromosome abnormalities is irreversible ,so the chromosome cytogenetic examination is especially important in the diagnosis and treatment process of infertile patients .
