Comparison of CT performance of hepatocellular carcinoma with postoperative pathology and its relationship with vascular endothelial growth factor
10.3969/j.issn.1002-1671.2016.07.018
- VernacularTitle:肝细胞癌CT表现与手术病理对照及其与血管内皮生长因子表达的关系
- Author:
Yingning WU
;
Yumin LU
;
Hengguo LI
;
Qunying SU
- Publication Type:Journal Article
- Keywords:
hepatocellular carcinoma;
computed tomography;
vascular endothelial growth factor
- From:
Journal of Practical Radiology
2016;32(7):1063-1065,1084
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare CT performance of the hepatocellular carcinoma (HCC)with postoperative pathology and to probe their relationships with vascular endothelial growth factor (VEGF)expression in order to provide more information for the treatment.Methods Clinical data of 75 patients with HCC were enrolled,including preoperative plain and enhanced CT scans,post-operative results of HE staining and immunohistochemical one of VEGF.The CT manifestations were compared with the pathological results of the HCC,and the relationship of CT findings and the VEGF expression was anlyzed.Results There was significant differ-ence between the liver cirrhosis or lymph node enlargement on CT in 75 patients with HCC and the pathology (P <0.05);However the tumor diameter,tumor emboli of portal vein and hepatic vein on CT were similar to those in pathology,exhibiting no statistically significant difference (P >0.05).The psuedocapsule of HCC,tumor size,pathological blood vessel,and tumor necrosis were related with the VEGF expression (P <0.05);However the tumor emboli of portal vein and hepatic vein,cirrhosis of the liver and intrahe-patic lesions (single or multiple)and lymph node enlargement were not related with VEGF expression (P >0.05).Conclusion The CT manifestations of HCC are closely related to the expression of VEGF.CT may reflect the pathological and biological characteris-tics of HCC with some limitations.
