Analysis of immunophenotype results in 5 patients with acute megakaryoblastic leukemia
10.3969/j.issn.1673-4130.2016.15.009
- VernacularTitle:5例急性巨核细胞白血病患者免疫表型结果分析
- Author:
Jiangyong YANG
- Publication Type:Journal Article
- Keywords:
acute megakaryoblastic leukemia;
cell surface differentiation antigens;
immunophenotype
- From:
International Journal of Laboratory Medicine
2016;37(15):2074-2075,2078
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the role of various blood cell surface differentiation antigens (CD) in the diagnosis and differen‐tial diagnosis of acute megakaryoblastic leukemia by detecting the immunophenotype in 5 patients with acute megakaryoblastic leu‐kemia .Methods The flow cytometry produced by the BD company and its matching reagents kits were used to detect CD in 5 pa‐tients with acute megakaryoblastic leukemia .Results All patients expressed CD41 and CD42 with the positive rate of 100% ;the lymphoid antigens ware negative in all cases ;CD13 was positive in 4 cases with the positive rate of 80% ;CD33 was positive in 3 ca‐ses with the positive rate of 60% ;CD14 and CD15 were expressed in each 1 case ,the positive rate was 20% .Conclusion The test results show that the CD41 and CD42 have an important value in the diagnosis and differential diagnosis of acute megakaryoblastic leukemia .At the same time ,the characteristic of series non‐specificityin the blood cells of the patients with acute megakaryoblas‐tic leukemia is verified again .
