PCR analysis and molecular characters of the first serogroup W135 meningococcal disease case in Shanxi province
10.3760/cma.j.issn.1008-6706.2016.16.022
- VernacularTitle:山西省首例W135群流行性脑脊髓膜炎的PCR鉴定及多位点测序分型分析
- Author:
Suxia YAO
;
Ruie HAO
;
Qiuxiang ZHANG
;
Hongxia YANG
- Publication Type:Journal Article
- Keywords:
Neisseria meningitides;
Encephalomyelitis;
Genetic testing
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;23(16):2485-2486,2487
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the PCR and molecular characters of the first serogroup W135 meningo-coccal death case in Shanxi province on April,2013.Methods Epidemiological survey of suspected epidemic cere-brospinal meningitis case was conducted,blood serum and petechia tissue fluid samples were identified by PCR for crgA gene and siaD gene of W 135.Multilocus sequence typing(MLST)was performed for determining the sequence types(STs).Results The patient in the case died of serogroup W135 Neisseria meningitides,which belonged to ST-11.Conclusion This is the first case died of serogroup W135 Neisseria meningitidis in Shanxi province,which prompts that the surveillance of meningococcal pathogeny should be strengthened.
