Analysis on correlation between glycosylated hemoglobin control situation and hemorheological indicators in diabetes patients
10.3969/j.issn.1673-4130.2016.14.003
- VernacularTitle:糖尿病患者糖化血红蛋白控制情况与血液流变学指标相关性分析
- Author:
Min LUO
;
Keqin QING
- Publication Type:Journal Article
- Keywords:
diabetes;
glycated hemoglobin;
hemorheology
- From:
International Journal of Laboratory Medicine
2016;37(14):1907-1908,1911
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between the glycosylated hemoglobin (HbA1c) detection data and hemo‐rheological indicators in diabetes patients to provide reference basis for its treatment and prevention .Methods One hundred and forty‐two patients with typeⅡdiabetes mellitus(T2DM ) in the hospital were selected as the research subjects and divided into the A group(69 cases ,better control) and B group(73 cases ,poor control) according to the HbA1c detection results .Contemporaneous 70 healthy individuals undergoing physical examination were selected as the control (C group) .The detection results of HbA1c ,hemo‐rheology and biochemical indexes were performed the contrastive analysis .Results Except hematocrit and erythrocyte deformation index without statistical difference among 3 groups(P>0 .05) ,the other hemorheologic indicators had statistical differences among 3 groups(P<0 .05) .No matter the HbA1c level in T2DM patients ,the hemorheological indexes ,triglyceride and total cholesterol were higher than those in the healthy people ,When the HbA1c leve was poorly controlled ,the increase degresss of various indexes were more significant .Conclusion The abnormality of hemorheology indices exist in most of the patients with diabetes mellitus .It is recommended that clinic should monitor the HbA1c level for long term and strictly observe the change of hemorheology indexes to guide the clinical treatment for reaching the effects of early vascular protection and prevention of diabetic complications .
