Level set motion-based elastic registration of 3D CT images in radiotherapy

VernacularTitle:基于水平集的三维放射治疗CT图像弹性配准
Author: Xiangxiang SHI ; Tao TANG ; Haowen PANG
Publication Type:Journal Article
Keywords: Level set motion; Elastic registration; Radiotherapy
From: China Medical Equipment 2016;13(7):20-21,22
CountryChina
Language:Chinese
Abstract: Objective: To apply level set motion-based elastic registration method to radiotherapy CT image, then to provide technical support for the accurate evaluation of tumor and changing process of patients with endanger organ and its accumulative dose. Methods: Based on Vemuri’s level set motion method, we wrote the algorithm program using Matlab software and applied on two sets of 3D CT images from patients with cervical cancer and NPC for fully automatic elastic registration. Results: Comparing CT images before and after registration, for the cervical cancer patient, the minimum mean square error (MSE) decreased by 55.1%and correlation coefficient (CC) increased by 5.3%. For the NPC patient, MSE decreased by 32.1%and CC increased by 4.6%. Conclusion: From the image difference and evaluation parameters, the efficacy of level set motion-based elastic registration method was preliminarily demonstrated. In order to apply this method to clinical radiotherapy, dit needs to find a more accurate mathematical algorithm further in order to compute human anatomy deformation through image motion.