Correlation between the follicle-stimulating hormone receptor gene polymorphism and the ovarian ;hyperstimulation syndrome
10.3969/j.issn.1006-5725.2016.12.030
- VernacularTitle:卵泡刺激素受体基因多态性与卵巢过度刺激综合征的相关性
- Author:
Ya SHEN
;
Li CHEN
;
Xiaofang TAN
;
Jingjing ZHANG
;
Weihong SHI
- Publication Type:Journal Article
- Keywords:
Follicle-stimulating hormone receptor;
Ovarian hyperstimulation syndrome;
Single nucleotide polymorphism
- From:
The Journal of Practical Medicine
2016;32(12):1994-1996,1997
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between OHSS and FSHR gene polymorphism. Methods Two hundred and two women were enrolled in this study. The FSHR gene polymorphisms at position 307 and 680 were detected. Results The distribution of the allele frequency and genotype frequency of the position 680 in FSHR gene were significantly different between women with OHSS or not. No significant differences of the position 307 in FSHR gene were observed. Conclusion Themutation of Asn680Ser in FSHR might be closely related with OHSS.
