The early diagnosis of lung cancer tumor -associated substance group and ferritin bronchoalveolar lavage fluid
10.3760/cma.j.issn.1008-6706.2016.15.012
- VernacularTitle:支气管肺泡灌洗液中恶性肿瘤特异性生长因子和铁蛋白对肺癌的早期诊断价值
- Author:
Wei YE
- Publication Type:Journal Article
- Keywords:
bronchoalveolar lavage;
Tumor group;
Ferritin;
lung cancer
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;23(15):2282-2284,2285
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the early diagnosis of lung cancer in bronchoalveolar lavage fluid (BALF) in tumor -related substance groups (TSGF)and ferritin (SF),in order to provide a theoretical basis for clinical application.Methods 40 patients with lung cancer and 40 patients with benign lung disease were selected as the study objects,who were collected fasting blood and bronchoalveolar lavage fluid,using chemistry colorimetry to detect TSGF,using radioimmunoassay to detect SF.Results The serum TSGF,SF in the lung cancer patients were (80.43 ± 6.32)U /mL and (254.55 ±13.43)μg/L,which were significantly higher than the pulmonary benign lesion group (t =6.89,9.33,all P <0.05).The bronchoalveolar lavage fluid TSGF,SF in the lung cancer patients were (140.32 ± 11.45)U /mL and (365.87 ±23.65)μg/L,which were significantly higher benign than lung disease group(t =7.65, 12.38,all P <0.05).Bronchoalveolar lavage fluid TSGF and SF in patients with lung cancer were significantly higher than the serum,the difference were significant(t =7.41,8.94,all P <0.05).Conclusion Bronchoalveolar lavage fluid TSGF,SF detect for early diagnosis of lung cancer has a certain value,which were significantly better than the serum.So it can be clinically applicated.
