The relationship between atherosclerotic cerebral infarction patients plasma oxidized low density lipoprotein and vascular endothelial injury degree
10.3760/cma.j.issn.1008-6706.2016.15.022
- VernacularTitle:动脉粥样硬化性脑梗死患者血浆氧化低密度脂蛋白与血管内皮损伤程度的关系
- Author:
Yanli ZHANG
- Publication Type:Journal Article
- Keywords:
Cerebral Infarction;
Endothelial Cells;
Lipoproteins,LDL;
Coronary Artery Disease
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;23(15):2318-2320,2321
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the difference of cerebral infarction patients plasma oxidized low density lipoprotein,circulating endothelial cells,nitric oxide levels and normal people,and study the correlation detection index.Methods 50 patients with cerebral infarction were selected as the observation group,21 cases of normal people were selected as the control group.The oxidized low density lipoprotein,circulating endothelial cells,and nitric oxide were detected.Results The plasma oxidized low density lipoprotein,circulating endothelial cells,nitric oxide levels of the observation group were (687 ±169)μg/L,(9.0 ±1.7)cells/0.9 μL,(52.3 ±16.6)μmol/L respec-tively,which of the control group were (350 ±173)μg/L,(2.5 ±0.5)cells/0.9 μL,(77.4 ±21.1)μmol/L,there were statistifically significant differences between the two groups(t =5.278,8.982,4.371,all P <0.05).Correlation analysis showed that ox -LDL and NO(P =0.013,r =0.782),ox -LDL and CEC(P =0.019,r =0.793),CEC and NO(P =0.021,r =0.952),there were significant correlation.Conclusion Vascular endothelial injury degree will affect the plasma oxidized low density lipoprotein in patients with test results,so the clinical treatment should pay attention to the protection and antiinflammatory treatment on the function of endothelial cells.
