The clinical study of the effect of the treatment of the knee joint replacement with Rivaroxaban
10.3760/cma.j.issn.1008-6706.2016.15.025
- VernacularTitle:利伐沙班用于髋、膝关节置换术后抗凝效果的临床观察
- Author:
Weiguo HU
;
Yao YUAN
- Publication Type:Journal Article
- Keywords:
Arthroplasty,Replacement,Hip;
Arthroplasty,Replacement,knee;
Rivaroxaban;
Anticoagulation
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;23(15):2328-2330,2331
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of the application of Rivaroxaban in the treatment of the patients with total hip replacement.Methods 114 patients with total knee arthroplasty were randomly divided into control group and observation group,57 cases in each group.All patients were operated by the standard operation in the department of orthopedics.The control group was given low molecular weight heparin before operation.The patients in the observation group were treated with 8h after the operation,and the color Doppler ultrasound was performed on the patients with double lower limbs and lungs after 2 courses of treatment.Observation of drainage,two groups of patients after total blood transfusion,blood index,adverse reactions and deep vein thrombosis cases.Results In the observation group,the deep vein embolism rate (1.75%)was significantly lower than that in the control group of 12.28% (χ2 =4.25,P <0.05 );The postoperative drainage volume,blood transfusion and blood index of the two groups had no significant differences (t =0.57,0.82,1.03,all P >0.05).During the treatment,the patients in the two groups were adverse reactions.Conclusion The effect of oral administration of Rivaroxaban after hip replacement surgery is remarkable,which can effectively reduce the incidence of deep venous thrombosis,and it is safe,and it is worthy of clinical application.
