Study on serum C -reactive protein,plasma fibrinogen,D -dimer in the first onset young patients with acute progressive cerebral infarction
10.3760/cma.j.issn.1008-6706.2016.14.028
- VernacularTitle:初次发病的中青年急性期进展性脑梗死患者血清 C 反应蛋白、血浆纤维蛋白原、D-二聚体水平研究
- Author:
Yuhong YANG
;
Zhimin ZHANG
;
Dayan HE
- Publication Type:Journal Article
- Keywords:
Brain infarction;
C -reactive protein;
Fibrinogen;
Young
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;23(14):2186-2188,2189
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the levels of serum C -reactive protein (CRP),plasma fibrinogen (Fib),D-dimmer(DD)in the first onset young patients with acute progressive cerebral infarction.Methods 42 first onset young patients with acute progressive cerebral infarction(PIS group),50 cases of non -acute progressive cerebral infarction(N -PIS group)and 90 healthy people(health control group)were enrolled.The levels of serum CRP, plasma Fib and DD were detected and compared.Results PIS group:CRP (3.764 ±0.832)mg /L,Fib (3.994 ± 0.851)g/L,DD (1.560 ±0.225)μg/mL;N -PIS group:CRP (2.573 ±0.657)mg/L,Fib (2.468 ±0.739)g/L, DD (0.740 ±0.162)μg/mL;health control group:CRP (1.725 ±0.326)mg/L,Fib (2.103 ±0.584)g/L,DD (0.450 ±0.131)μg/mL.The levels of serum CRP,plasma Fib and DD of PIS group were higher than the other two groups(CRP:PIS group vs.N -PIS group t =8.89,PIS group vs.health control group t =13.99,N -PIS vs.health control group t =8.55,all P <0.01;D -D:PIS group vs.N -PIS group t =23.82,PIS group vs.health control group t =29.46,N -PIS group vs.health control group t =12.59,all P <0.01;FIB:N -PIS group vs.health control group t =2.85,P <0.05,PIS group vs.N -PIS group t =10.06,PIS group vs.health control group t =13.48,all P <0.01).Conclusion The levels of serum CRP,plasma Fib and DD are related to acute progressive cerebral infarction.
