Progresses of vascular endothelial growth factor as a target for acute myeloid leukemia therapy
10.3760/cma.j.issn.1008-6315.2016.07.024
- VernacularTitle:血管内皮细胞生长因子靶向治疗急性髓系白血病的研究进展
- Author:
Xiaojuan HE
;
Liefen YIN
- Publication Type:Journal Article
- Keywords:
Vsscular endothelial cell growth factor;
Acute myeloid leukemia;
Vascularization
- From:
Clinical Medicine of China
2016;32(7):659-661,662
- CountryChina
- Language:Chinese
-
Abstract:
Objective Vascular endothelial growth factor( VEGF) is the key to regulat vascularization, and plays an important role in the development of acute myeloid leukemia. With the understanding of anti?tumor angiopoiesis, researchers take VEGF and its receptors as targets, continuously exploring the new drug. We summarized the biological characteristics of VEGF, vascular?targeted therapy and the clinical application of drugs.