The progess of the hypercytokinemia in the children with hemophagocytic syndrome
10.3760/cma.j.issn.1008-6706.2016.12.039
- VernacularTitle:高细胞因子血症在儿童噬血细胞综合征中的研究进展
- Author:
Fangling DONG
;
Shufang XIAO
- Publication Type:Journal Article
- Keywords:
Lymphohistiocytosis,hemophagocytic;
Children
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;23(12):1901-1903,1904
- CountryChina
- Language:Chinese
-
Abstract:
Hemophagocytic lymphohistiocytosis(HLH)is a disease caused by various pathogenic factors and characterised by activated lymphoid cells and tissue cells,which release massive cytokines and results in hypercytoki-nemia and severe functional distraction of visceral organs.The disease is classified to primary/inherited HPS and sec-ondary/reactive HPS.The hypercytokinemia play a key role in the process of disease development.In this article,the hypercytokinemia in the pathogenesis of children HLH was reviewed.