Clinical observation of using transcervical resection of adhesion (TCRA)combined with reinforcing kidney and removing stasis to treat intrauterine adhesion
10.3760/cma.j.issn.1008-6706.2016.09.002
- VernacularTitle:宫腔粘连分离术联合补肾化瘀法治疗清宫术后宫腔粘连的临床观察
- Author:
Lijun CHEN
- Publication Type:Journal Article
- Keywords:
Tissue adhesions;
Hysteroscopy;
Medicine,Chinese traditional
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;23(9):1284-1287,1288
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the clinical effects and mechanism of using transcervical resection of adhesion (TCRA)combined with reinforcing kidney and removing stasis to treat intrauterine adhesion.Methods From June 2014 to December 2014,70 patients with intrauterine adhesion were selected in our hospital and randomly divided into the observation group and the control group (35 cases in each group).All the two groups had TCRA.The observation group had reinforcing kidney and removing stasis method,while the control group had climen treatment. Both two groups had 3 menstrual cycles of treatment.After treatment,the overall curative effect,menstruation recovery analysis caused by intrauterine adhesions degree before and after treatment and the endometrium,serum E2,FSH and uterine artery blood flow pulsation index and resistance index of the two groups were recorded and compared.Results After 3 menstrual cycles after treatment,the total effective rate in the observation group was 94.3%,which was significantly higher than 7 7 .1 % in the control group (χ2 =4 .2 0 0 ,P <0 .0 5 ).And the primary symptom menstruation recovery rate in the observation group was 97.2%,which was significantly higher than 82.8% in the control group (χ2 =3.968,P <0.05).After treatment,the IUA integral scores in the two groups had significant reduction (t =6.50,3.36,all P <0.05),but the observation group decreased more obviously (t =3.82,P <0.05). After treatment,RI in the two groups declined more significantly compared with before treatment (t =2.23,1.70,all P <0.05),but PI without statistically significant difference compared with before treatment (t =0.38,0.65,all P >0.05).After treatment,the uterine artery blood flow of PI,RI had no statistically significant differences between the two groups (t =0.42,0.56,all P >0.05).During treatment,the heart,liver,kidney,blood and urine routine in two groups were all within the normal range,and the incidence rate of adverse reactions was 11.4% in the control group, which was significantly higher than 2.8% in the observation group (χ2 =3.968,P <0.05 ).Conclusion Using TCRA combined with reinforcing kidney and removing stasis to treat intrauterine adhesion after treatment has better curative effects,which could promote the menstrual cycle of uterine cavity formation and recovery.Its mechanism may be related to uterine blood flow perfusion improvement and womb restoration.