Effect of Modified Decoction for treating lung -qi and spleen -qi deficiency syndrome in patients with stable chronic obstructive pulmonary disease
10.3760/cma.j.issn.1008-6706.2016.05.018
- VernacularTitle:加减补肺汤治疗慢性阻塞性肺疾病稳定期肺脾气虚证患者的疗效分析
- Author:
Shihong YANG
;
Xue LI
- Publication Type:Journal Article
- Keywords:
Pulmonary disease,chronic obstructive;
Stable stage;
Lung -qi and spleen -qi deficiency syndrome;
Modified Bufei decoction;
Clinical effect
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;23(5):708-711,712
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe and analyze the clinical effect of Modified Decoction for the treatment of lung -qi and spleen -qi deficiency syndrome in patients with stable stage of chronic obstructive pulmonary disease (COPD).Methods 86 patients with lung -qi and spleen -qi deficiency syndrome in stable stage of COPD were divided into the observation group (n =43) and control group (n =43) according to a random number table method. The control group was treated with conventional western medicine therapy,the observation group was given modified Bufei decoction treatment on the basis of western medicine treatment.The clinical therapeutic effect of two groups was assessed.Results The effective rate of the observation group was 83.72%,which was significantly higher than 72.09% of the control group,the difference was statistically significant (χ2 =3.9289,P <0.05).After treatment,the FEV1 ,FEV1 /FVC,FEV1% expected values of the two groups were significantly higher than those before treatment (t =3.6984,3.6915,3.7431,4.2675,4.6821,5.0567,all P <0.05).After treatment,the FEV1 ,FEV1 /FVC, FEV1% predicted value of the treatment group were (2.45 ±0.35)L/s,(63.91 ±7.42)%,(47.29 ±7.52),which were significantly higher than those of the control group (t =3.6884,3.7581,4.1957,all P <0.05).After treatment, the levels of IL -8 and TNF -αwere not significantly changed in the control group.The levels of IL -8 and TNF -αin the observation group were significantly lower than those in the control group (t =8.864,9.571,all P <0.05). Conclusion In COPD patients of stable stage with lung -qi and spleen -qi deficiency syndrome,plus or minus fill lung soup can effectively relieve clinical symptoms and improve pulmonary function of patients,reduce the acute attack,and improve the quality of life of patients,it is worthy of clinical application.
