Analysis of the Correlation between the Use Density of Antibiotic and Antifungal Drugs and the Positive Rate of Aspergillus
10.3870/j.issn.1004-0781.2016.04.0
- VernacularTitle:抗菌药物和抗真菌药物使用强度与曲霉菌阳性率相关性分析
- Author:
Chengchun SUN
;
Lili YU
;
Jixia LI
;
Lingling BI
;
Jianjiang XU
- Publication Type:Journal Article
- Keywords:
Antibiotics;
Antifungal drugs;
Use density;
Aspergillus;
Correlation
- From:
Herald of Medicine
2016;35(4):415-417,418
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between the use density of antibiotic and antifungal drugs and the positive rate of aspergillus in our hospital from 2009 to 2013,in order to provide a scientific basis for rational use of antibiotic and antifungal drugs. Methods The use density of carbapenems,two third-generation cephalosporins,and antifungal drugs,and the positive rate of aspergillus in our hospital from 2009 to 2013 were studied retrospectively. Their correlation was analyzed using SPSS software. Results There was significantly positive correlation between the use density of imipenem and that of fluconazole (r=0.913,P<0.05).The use density of biapenem was positively correlated with that of voriconazole (r=0.915,P<0.05).The use density of biapenem and that of voriconazole was positively correlated with positive rate of aspergillus,respectively ( r=0.918,r=0.955,both P<0.05).The other antibiotic and antifungal drugs were not significantly correlated to the positive rate of aspergillus.
