The analyse of examining the bone marrow involvement in ninety-three patients of non-Hodgkin′s lymphoma

VernacularTitle:93例B细胞非霍奇金淋巴瘤患者骨髓受累的诊断分析
Author: Wenbin QIAO ; Wei YE ; Yanchun HUANG
Publication Type:Journal Article
Keywords: non-Hodgkin′s lymphoma; flow cytometry; bone marrow involvement
From: International Journal of Laboratory Medicine 2016;37(9):1175-1176,1179
CountryChina
Language:Chinese
Abstract: Objective To explore the value of combined detection of bone marrow smear(BMS) and flow cytometry(FCM) to examine bone marrow involvement(BMI)of B cell non‐Hodgkin′s lymphoma(B‐NHL) .Methods Patients with B‐NHL were detec‐ted by BMS and FCM simultaneously .Smears were stained with Wright‐Giemsa′s staining to differentially count neoplastic cells and the processed sample with fluorescent staining for the FCM .Results 93 cases of patients with B‐NHL were detected .The detection rate of BMS and FCM were 11 .8% and 29 .0% .There was statistical difference of detection rate between the two method(P<0 .05) .In 11 cases patients of BMI with the method of BMS ,while using the method of FCM 10 cases were positive .Conclusion Both BMS and FCM are useful to diagnose BMI of B‐NHL ,each of them has individual characteristics .Combined detection of these two methods can increase the diagnostic of BMI .