Methicillin-resistant Staphylococcus aureus SCCmec parting and resistance analysis
10.3969/j.issn.1673-4130.2016.04.009
- VernacularTitle:耐甲氧西林金黄色葡萄球菌的SCCmec分型及耐药性分析
- Author:
Yu WU
;
Guiyu WANG
;
Yao YU
;
Li XU
;
Junfu HUANG
- Publication Type:Journal Article
- Keywords:
Staphylococcus aureus;
anti-methicillin-resistant;
drug resistance
- From:
International Journal of Laboratory Medicine
2016;37(4):455-456,458
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical distribution ,antimicbial resistance and Staphylococcal cassette chromosome mec (SCCmec) genotype characteristics of 346 methicillirrresistant Staphylococcus aureus (MRSA) clinical isolates in the hospital . Methods A total of 784 strains of Staphylococcus aureus isolated from January 2014 to January 2015 in the hospital ,MRSA identi-fication and the SCCmec genotype was conducted by PCR assay .Results 346 strains of MRSA (44 .13% ) were isolated from 784 strains of Staphylococcus aureus ,the detection rate of MRSA from sputum accounted for 43 .06% ,the secretion accounted for 48 .55% .MRSA was resistant to penicillin ,levofloxacin and erythromycin ,sensitive to vancomycin ,linezolid and teicoplanin .SCC-mec genotyping result showed that SCCmecⅡ was identified in 130 ,SCCmecⅢ in 196 ,SCCmecⅣ in 11 ,SCCmecⅤ in 9 .Conclusion SCCmecⅢ is the main genotypes of MRSA from our Hospital ,all of the MRSA strains are multi-resistant to tested antibiotics , but sensitive to vancomycin and teicoplanin .
