The treatment effect of Shah Mette Lo/fluticasone inhalation for stable stage of chronic obstructive pulmonary disease
10.3760/cma.j.issn.1008-6706.2015.s2.007
- VernacularTitle:沙美特罗／替卡松粉吸入剂对慢性阻塞性肺疾病稳定期的治疗作用
- Author:
Hongbin SU
;
Ling LIU
;
Hui GAO
;
Li LIU
- Publication Type:Journal Article
- Keywords:
Pulmonary Disease,Chronic Obstructive;
Albuterol;
Budesonide;
Shah Mette Lo /fluticasone propionate;
Treatment Outcome
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;(z2):16-17,18
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the treatment effect of Shah Mette Lo/fluticasone inhalation(Seretide)for stable stage of chronic obstructive pulmonary disease (COPD).Methods 50 patients with COPD were randomly divided into treatment group and control group.The treatment group was given Seretide (specifications of 250μg)1 -2 ceiling/time,2 times/day,after 24 weeks of treatment,the control group was given 2mg of regular salbutamol com-bined with budesonide 1mg atomization inhalation,2 times daily.The clinical symptoms were compared before and aftertreatment.Results In the treatment group,acute seizure frequency was significantly reduced,cough,wheezing singing decreased or disappeared,self -care ability improved,the control group had no obvious change.The control group:before treatment FEV1 (1.1 ±0.4)L;FEV1 % predicted value(22.5 ±5.1 )%;FEV1 /FVC%:(25.3 ±5.8)%;after treatment FEV1 (1.5 ±0.7)L;FEV1 % predicted value(29.4 ±6.2)%;FEV1 /FVC%:(32.8 ±6.6)%.The treatment group:before treatment FEV1 (1.1 ±0.6)L;FEV1 % predicted value (24.5 ±5.6)%;FEV1 /FVC%:(26.7 ±6.6)%;after treatment FEV1 (1.7 ±0.6)L;FEV1 % predicted value(33.4 ±7.8)%;FEV1 /FVC%:(37.8 ± 8.6)%.Conclusion In patients with stable COPD inhaled Seretide treatment can significantly improve lung func-tion,and it is better than sardine an alcohol combined with budesonide inhalation therapy.
