Clinical observation of methylprednisolone in the treatment of chidren with severe Mycoplasma pneumoniae pneumonia
10.3760/cma.j.issn.1008-6706.2015.s2.009
- VernacularTitle:甲泼尼龙联合大环内酯类抗生素治疗小儿重症肺炎支原体肺炎临床观察
- Author:
Lingli PENG
- Publication Type:Journal Article
- Keywords:
Mycoplasma pneumoniae pneumonia;
Methylprednisolone;
Child
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;(z2):21-22,23
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy of methylprednisolone in the treatment of chidren with severe Mycoplasma pneumoniae pneumonia(MPP).Methods 100 children with severe MPP were divided into con-trol group and treatment group.The control group was given to macrocyclic lactone antibiotics,symptomatic and sup-portive and other conventional treatment.The treatment group was given to Methylprednisolone dose for 2mg·kg -1 ·d -1 ×5d at the base of the control group.The clinical manifestations,such as the time of reducing cough,the tem-perature dropped to normal time,pulmonary rales disappeared time,affection absorption time,as well as length of the stay were observed.Results The time of reducing cough,temperature dropped to normal time,pulmonary rales disap-peared time and the affection absorption time of the treatment group were (5.46 ±2.03)days,(3.35 ±1.79)days, (7.08 ±2.56)days,(7.89 ±1.44)days,(10.15 ±2.03)days respectively,which of the control group were (4.23 ± 1.59)days,(5.00 ±2.30)days,(9.07 ±1.9)days,(9.23 ±1.64)days,(12.76 ±2.03)days respectively.The tem-perature dropped to normal time,pulmonary rales disappeared time and the affection absorption time of the treatment group were shorter than the control group(all P <0.05),but the time of reducing cough between the two groups had no significant difference(P >0.05).There was significant difference in cure rate between the two groups(χ2 =5.488, P <0.05).Conclusion The efficacy of methylprednisolone therapy for children with grave Mycoplasma pneumoniae pneumonia(MPP)is affirmation,worthy of clinical application.
