Statistical basis for pharmacometrics: random variables and their distribution functions, expected values, and correlation coefficient.
10.12793/tcp.2016.24.2.66
- Author:
Kyungmee CHOI
1
Author Information
1. Division of Mathematics, College of Science and Technology, Hongik University at Sejong, Jochiwon, Sejong 30016, South Korea. kmchoi@hongik.ac.kr
- Publication Type:Review
- Keywords:
Probability;
Expected values;
Moment generating function;
Correlation coefficient
- MeSH:
Mathematics;
Numismatics;
Probability Theory
- From:Translational and Clinical Pharmacology
2016;24(2):66-73
- CountryRepublic of Korea
- Language:English
-
Abstract:
For pharmacometricians, probability theory is the very first obstacle towards the statistics since it is solely founded on mathematics. The purpose of this tutorial is to provide a simple version of introduction to a univariate random variable, its mean, variance, and the correlation coefficient of two random variables using as simple mathematics as possible. The definitions and theorems in this tutorial appear in most of the statistics books in common. Most examples are small and free of subjects like coins, dice, and binary signals so that the readers can intuitively understand them.
