The value of quantitative TB-DNA test,interferon gamma release test,tuberculosis antibody detection in the pulmonary tuberculosis smear positive patients
10.3969/j.issn.1673-4130.2016.02.028
- VernacularTitle:涂阳肺结核患者 TB-DNA 定量、γ干扰素释放试验、结核抗体检测的价值
- Author:
Hui LI
;
Jin TANG
;
Xiaoxia HUANG
- Publication Type:Journal Article
- Keywords:
tuberculosis,pulmonary/diagnosis;
mycobacterium tuberculosis;
staining and labeling;
microscopy;
quanti-tative TB-DNA;
interferon gamma release test;
tuberculosis antibody
- From:
International Journal of Laboratory Medicine
2016;(2):211-212,215
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of quantitative TB‐DNA test ,interferon gamma release test and the detection of tuberculosis antibodies for the diagnosis of active pulmonary tuberculosis .Methods 51 patients were diagnosed as tuberculosis from 2013 July to 2014 June in the hospital ,whose sputum smear microscopy for acid fast bacilli were positive .Then TB‐DNA quantitative test ,interferon gamma release test (T‐SPOT .TB)and tuberculosis antibody detection were performed for those pa‐tients .All the result were retrospectively analysed .Results The positive rate of T‐SPOT .TB was 90 .1% ,the positive rate of quan‐titative TB‐DNA test was 74 .5% and the positive rate of tuberculosis antibody detection was 37 .3% .Conclusion Because the re‐sult of T‐SPOT .TB is not affected by the process of specimen collection ,it is the most sensitive test of the three tests at present , and has higher value in the auxiliary diagnosis of active pulmonary tuberculosis than the other two .
