The correlation studies of the Lp-PLA2,hs-CRP and D-dimmer in patients with coronary heart disease
10.3969/j.issn.1673-4130.2016.02.009
- VernacularTitle:冠心病患者血液Lp-PLA2、hs-CRP及D-二聚体检测的相关性分析
- Author:
Qiong CHEN
;
Minxiao WU
;
Hongbin CHEN
;
Zhangyuan RUAN
- Publication Type:Journal Article
- Keywords:
coronary disease;
1-alkyl-2-acetylglycerophosphocholine esterase;
C-reactive protein;
D-dimer
- From:
International Journal of Laboratory Medicine
2016;(2):164-165,168
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the correlations among the lipoprotein associated phospholipase A2 (Lp‐PLA2) ,hypersensitive C‐reactive protein(hs‐CRP)and D‐dimmer in patients with the coronary heart disease .Methods 260 cases of patients with coronary heart disease(CHD) were enrolled in the study as observation group and 260 healthy people from the physical examinations were recruited as control group .The concentrations of Lp‐PLA2 ,hs‐CRP ,D‐dimer and other biochemical indicators in blood sera of the two groups were detected ,using the Spearman correlation analysis to test the relationship between those indicators .Results The Lp‐PLA2 ,hs‐CRP ,D‐dimer levels of the observation group were obviously higher than those of control group .The Lp‐PLA2 level of the observation group was positively correlated with the cardiac function index(r=0 .873 ,P<0 .05) .hs‐CRP was positively cor‐related with cardiac function index(r=0 .782 ,P<0 .05) .D‐dimmer was positively correlated with the functional grades of heart(r=0 .674 ,P<0 .05) .Conclusion Lp‐PLA2 ,hs‐CRP and D‐dimer could be important indicators for the detection of coronary heart disease .
