Application value of procalcitonin,C-reactive protein,prealbumi and white blood cell in children with hand-foot-and-mouth disease
10.3969/j.issn.1673-4130.2016.06.016
- VernacularTitle:降钙素原、C 反应蛋白、前清蛋白及白细胞计数在儿童手足口病诊断中的应用价值
- Author:
Guicheng YE
;
Jianming PENG
;
Yanfei GUAN
;
Bin YUAN
- Publication Type:Journal Article
- Keywords:
procalcitonin;
C-reactive protein;
prealbumi;
white blood cell count;
hand-foot-and-mouth disease
- From:
International Journal of Laboratory Medicine
2016;37(6):758-759,762
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the application value of procalcitonin (PCT ) ,C-reactive protein (CRP) ,prealbumi (PA ) and white blood cell count (WBC))in children with hand-foot-and-mouth disease (HFMD) .Methods A total of 209 children with HFMD were classified into ordinary group (171 patients) and severe group (38 patients) according to the condition of disease ,an-other 30 healthy children were selected as the control group .The levels of PCT ,CRP ,PA and WBC in the three groups were meas-ured and compared .Results The levels of PCT ,CRP ,PA and WBC of ordinary group were 0 .16(0 .08 - 0 .34)μg/L ,11 .7(5 .0 -19 .0)mg/L ,(142 .6 ± 38 .4)mg /L and (11 .3 ± 4 .6) × 129 /L respectively ,and those of severe group were 0 .26(0 .14 - 0 .92)μg /L , 18 .4(5 .3 - 41 .4) mg /L ,(125 .5 ± 32 .9)mg/L and (13 .0 ± 5 .6) × 129 /L respectively .The PCT ,CRP ,PA and WBC in ordinary group and severe group were significantly different with those in the control group (P < 0 .05) .The PCT ,CRP and PA in severe group had statistical differences compared with those in the ordinary group (P< 0 .05) .Conclusion PCT ,CRP ,PA and WBC could be used as reference indexes of inflammation in HFMD ,and could be used in the diagnosis of HFMD in children ,PCT and PA could be used to evaluate the severity of disease .
