The mechanisms of steroid resistance of children′s idiopathic nephrotic syndrome
10.3760/cma.j.issn.1673-4408.2016.01.007
- VernacularTitle:儿童肾病综合征激素耐药机制研究进展
- Author:
Linyan SHI
;
Qihua FENG
- Publication Type:Journal Article
- Keywords:
Idiopathic nephrotic syndrome;
Children;
Steroid resistance
- From:
International Journal of Pediatrics
2016;43(1):24-28,32
- CountryChina
- Language:Chinese
-
Abstract:
The resistance to steroid remains a major trouble in the treatment of idiopathic nephrotic syn-drome,and the mechanisms are complicated. Recent studys have shown that multidrug resistance gene l and P-glycoprotein170,glucocorticoid receptor,renal pathology,gene mutation and complications are all closely related to the resistance to steroid. This review is focused on the mechanisms of steroid resistance of children′s idiopath-ic nephrotic syndrome.
