Clinical Effect of Suhuang Zhike Capsules Combined with Montelukast on Cough Caused by Upper Respir-atory Infection
- VernacularTitle:苏黄止咳胶囊联合孟鲁司特治疗上呼吸道感染后咳嗽疗效观察
- Author:
Hedong XUE
;
Fangfang ZHU
- Publication Type:Journal Article
- Keywords:
Suhuang Zhike capsules;
Montelukast;
Cough after upper respiratory infection
- From:
China Pharmacist
2016;19(2):332-334,405
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the clinical efficacy of Suhuang Zhike capsules combined with montelukast in the treatment of cough caused by upper respiratory infection. Methods:Totally 120 patients with cough after upper respiratory infection were randomly divided into the treatment group (64 cases) and the control group (56 cases) by the random number table. The control group received Montelukast chewable tablets alone(10 mg,po qn), while the treatment group received Suhaung Zhike capsules(1. 35 g,po,tid) com-bined with Montelukast chewable tablets. The treatment course was 2 weeks, and the efficacy and adverse reactions between the two groups after the treatment were compared. Results:The significant efficiency and the total efficiency of the observation group were sig-nificantly highter than those of the control group, and the difference was statistically significant(P<0. 05). After the treatment, the cough symptom score and the expectoration symptom score of the two groups were decreased significantly than those before the treatment (P<0.05), both scores of the observation group were significantly lower than those of the control group after the treatment(P >0. 05). The incidence of adverse reactions of the two groups had no significant differencet(P<0. 05). Conclusion: As for the clinic efficacy, the combination of Suhaung Zhike capsules and Montelukast is significantly better than Montelukast therapy, and the combina-tion is an effective and safe treatment for cough after upper respiratory infection and worthy of promotion in clinical practice.