Effectiveness of clinical pharmacists 'intervention in antimicrobial prophylaxis in type Ⅰ incisional surgery
10.3969/j.issn.1671-9638.2016.04.013
- VernacularTitle:临床药师干预Ⅰ类切口手术抗菌药物预防性使用的效果评价
- Author:
Min TAO
;
Yuesheng ZHANG
- Publication Type:Journal Article
- Keywords:
clinical pharmacist;
intervention;
perioperative period;
type Ⅰ incisional surgery;
antimicrobial agent;
rational drug use
- From:
Chinese Journal of Infection Control
2016;15(4):269-271,276
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate effectiveness of clinical pharmacists'intervention in perioperative antimicrobial use in type Ⅰ incisional surgery.Methods Clinical data of 1398 patients undergoing type Ⅰ incisional surgery in a hospital between January and December 2014 were analyzed retrospectively,633 patients who underwent surgery between January and June were as pre-intervention group,765 patients who underwent surgery between July and December were as post-intervention group (clinical pharmacists were assigned to strengthen the management and control of rational antimicrobial use),antimicrobial prophylaxis between pre-intervention group and post-interven-tion group were compared.Results In pre- and post-intervention groups,antimicrobial prophylaxis were 56.71%and 28.37% respectively(χ2= 113.26,P<0.05). Rational selection rates of antimicrobial types were 60.45% and 89.86% respectively,rational rates of administration time were 49.58% and 82.49% respectively,the rates of anti-microbial prophylaxis course≤24 hours were 11.42% and 29.95% respectively,>24 hours were 88.58% and 70.05% respectively,combination antimicrobial use were 10.31% and 0 respectively,the differences between before and after intervention were all statistically significant (all P<0.05). Incidence of surgical site infection in pre-and post-intervention groups were 0.79% (5/633)and 0.26% (2/765)respectively(P= 0.255).Conclusion Through clini-cal pharmacists'intervention in perioperative antimicrobial prophylaxis in type Ⅰ incisional surgery,antimicrobial prophylax-is rate decreased dramatically,antimicrobial management is more standardized,scientific and systematic.
