Performance of T cell infected with Mycobacterium tuberculosis assay in diagnosis of smear and culture negative pulmonary tuberculosis
10.3969/j.issn.1673-4130.2016.08.008
- VernacularTitle:结核感染T细胞检测在菌阴性肺结核诊断中的应用价值
- Author:
Mei LUO
;
Guihui WU
;
Ming YANG
;
Ji YUE
- Publication Type:Journal Article
- Keywords:
T cell infected with Mybacterium tuberculosis assay;
smear and culture negative pulmonary tuberculosis;
sensitiv-ity;
sensitivity;
specificity
- From:
International Journal of Laboratory Medicine
2016;37(8):1035-1036,1038
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the application value of T cell infected with Mybacterium tuberculosis assay in diagnosis of smear and culture negative pulmonary tuberculosis .Methods In total ,145 patients with smear and culture negative pulmonary tu‐berculosis and 45 patients with non‐tuberculosis lung disease were enrolled in the study .All patients received T cell infected with Mybacterium tuberculosis test and sensitivity ,specificity ,positive predicted value ,negative predicted value of testing for the diagno‐sis of smear and culture‐negative TB patients were calculated .Results The sensitivity of specificity T cell infected with Mybacteri‐um tuberculosis assay in diagnosis of smear and culture negative pulmonary tuberculosis was 85 .5% ,the specificity was 84 .4% , positive predicted value was 94 .7% ,negative predicted value was 64 .4% .No statistical significance in age‐dependent groups(P>0 .05) .Conclusion T cell infected with Mybacterium tuberculosis assay has high positive predicted value in diagnosis of smear and culture negative pulmonary tuberculosis and is suitable for clinical auxiliary diagnosis .
