Effect of Danggui shaoyao powder combined with Sanhuang lotion fumigation on TGF-β1, IL-4 and IL-10 in chronic pelvic inflammatory disease
10.3969/j.issn.1005-1678.2016.04.40
- VernacularTitle:当归芍药散联合三黄洗剂熏洗对慢性盆腔炎患者TGF－β1、IL－4及IL－10的影响
- Author:
Min HE
;
Rong ZHENG
- Publication Type:Journal Article
- Keywords:
Danggui shaoyao powder;
Sanhuang lotion fumigation;
chronic pelvic inflammation;
TGF-β1;
IL-4;
IL-10
- From:
Chinese Journal of Biochemical Pharmaceutics
2016;36(4):130-131,134
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of Danggui shaoyao powder combined with Sanhuang lotion fumigation on serum TGF-β1,IL-4 and IL-10 in the treatment of chronic pelvic inflammatory disease.Methods 38 cases with chronic pelvic inflammatory disease were selected and divided into the control group (19 cases) and the experiment group(19 cases) according to the random number table.The control group were treated with Sanhuang lotion fumigation bath, the experiment group were treated on the basis of the control group with Danggui shaoyao powder, 10 days for a course of treatment, a total of two courses of treatment.The serum IL-4, IL-10, TGF-β1 and clinical efficacy were compared before and after treatmentbetweentwo groups.Results The total effective rate of the experiment group was 94.74%, which was higher than 84.21% of the control group(P<0.05).After treatment, the clinical symptom score in experiment group was lower than that in control group, the serum levels of IL-4 and TGF-β1 were lower than those in control group, the serum level of IL-10 was higher than that in control group (P<0.05).Conclusion Danggui shaoyao powder combined with Sanhuang lotion fumigation could decreases IL-4 and TGF-β1 levels, increase IL-10 level and improve the inflammatory state in the treatment of chronic pelvic inflammatory disease.
