The influence of injection rate and time resolution on dynamic contrast-enhanced MR imaging of glioma

VernacularTitle:注射速率及时间分辨率对胶质瘤动态增强的影响
Author: Yulong ZHANG ; Jinhua CHEN
Publication Type:Journal Article
Keywords: injection rate; time resolution; dynamic contrast-enhanced; glioma
From: Journal of Practical Radiology 2016;(2):292-294,304
CountryChina
Language:Chinese
Abstract: Objective To explore the influence of contrast agent injection rate and sequence time resolution on the dynamic contrast-enhanced MR iamging of brain glioma.Methods Fifty eight cases with suspected cerebral glioma were scanned on a Verio 3.0T MRI with the regular head sequences and DCE sequences.All the cases were divided into two groups.There were 41 cases in the regular group in which the injection rate was 3 mL/s and the time resolution was above 5.36 s.Another 1 7 cases were in the optimal group in which the injection rate was 4 mL/s and the time resolution was about 4 s.The DCE images of two groups were Postprocessed by the Tofts model analysis.The curve shape of AIF were evaluated and divided in to the excellent or the secondary level.Chi-square test was used to compare the results of two groups.Results The curve shape of optimal group was much better than that of regular group(P<0.05).Conclusion Speeding up the injection rate and the time resolution of DCE sequences would improve the image quality of DCE MRI of glioma.