Effect of Modified Sijunzi Decoction on Humoral Immunity of Rats with Exercise-induced Exhaustion
10.13359/j.cnki.gzxbtcm.2015.06.018
- VernacularTitle:加味四君子汤对运动力竭大鼠体液免疫能力的影响
- Author:
Lin YANG
;
Jing TAN
- Publication Type:Journal Article
- Keywords:
Exercise-induced exhaustion/TCD therapy;
Modified Sijunzi Decoction/pharmacology;
Immunoregulation;
Disease models,animal;
Rats
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2015;32(6):1052-1054,1058
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the influence of modified Sijunzi Decoction on the decrease of immune function of exercise-induced exhaustion rats. Methods Thirty SD rats were given adaptive training, and then 6 dead or non-adaptive rats were dropped out. The remaining 24 SD rats were randomly divided into normal group ( N= 8) , model group ( N = 8) , and modified Sijunzi Decoction group ( MSD group, N = 8) . Normal group did not receive any medication and took diet freely. The rats of model group and MSD group were orally given distilled water or modified Sijunzi Decoction 8 g per day respectively after the modeling by exercise-induced exhaustion. After 61 days, the serum was taken from the three groups, and immunoglobulin lgA, lgG, lgM, and complement C3,C4 were detected. Results The contents of immunoglobulins IgA, IgG, IgM and complements C3, C4 in MSD group were higher than those in the model group ( P<0.01) . Conclusion The decrease of immunity occurs in the process of exercise stress, but can be delayed by modified Sijunzi Decoction..