Analysis of Serum Inflammation Related Factors of Influenza A (H1N1) Patients with Epidemic Febrile Damp-heat Syndrome and Warm-heat Syndrome
10.13359/j.cnki.gzxbtcm.2015.01.001
- VernacularTitle:甲型H1N1流感温病湿热证与温热证患者血清炎症相关因子研究
- Author:
Fengling ZHENG
;
Wei WU
;
Ye LIU
;
Liang LI
;
Huanhuan LUO
- Publication Type:Journal Article
- Keywords:
Influenza;
Influenza A virus subtype H1N1;
Epidemic febrile damp-heat syndrome;
Epidemic febrile warm-heat syndrome
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2015;(1):1-3,9
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the serum inflammation related factors of influenza A ( induced by sub-type H1N1 virus) patients with epidemic febrile damp-heat syndrome and warm-heat syndrome. Results Fifty-six patients confirmed as influenza A ( H1N1) were differentiated into epidemic febrile damp-heat syndrome ( 36 cases) and epidemic febrile warm-heat syndrome (20 cases) . And then we observed the serum immune globulins IgM and IgG, interleukin-8 (IL-8), tumor necrosis factor alpha (TNF-ɑ), tumor growth factor beta 1 (TGF-β1), lipolysaccharide binding protein (LBP), Toll-like receptor 4 (TLR4) and soluble CD14 (sCD14) levels of the influenza A patients. Results Insignificant differences of serum IgM, IgG, IL-8, TNF-ɑand TGF-β1 levels were shown between epidemic febrile damp-heat syndrome patients and epidemic febrile warm-heat syndrome patients (P>0.05), but the differences of LBP, TLR4 and sCD14 were significant (P<0.05) .Conclusion Influenza A (H1N1) patients with epidemic febrile damp-heat syndrome have higher serum LBP, TLR4 and sCD14 levels than patients with epidemic febrile warm-heat syndrome, indicating that inflammatory reaction is severer in influenza A (H1N1) patients with epidemic febrile damp-heat syndrome.
