Analysis of multi-drug resistance and homology of Acinetobacter baumannii isolated from patients with explosive injury
10.3969/j.issn.1673-4130.2015.23.002
- VernacularTitle:爆炸伤患者分离鲍曼不动杆菌的耐药性及同源性分析
- Author:
Yang LI
;
Wanqing ZHOU
;
Xiaoli CAO
;
Li SHEN
;
Yihong JIANG
- Publication Type:Journal Article
- Keywords:
explosive injury;
Acinetobacter baumannii;
multidrug-resistant;
homology analysis
- From:
International Journal of Laboratory Medicine
2015;(23):3367-3368,3371
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the drug resistance and homology of Acinetobacter baumannii (Ab) isolated from patients with explosive injury ,so as to explore the characteristics of drug resistance and prevalence of infection .Methods A total of 61 strains of AB isolated from clinical specimens of patients with explosive injury were collected .The antimicrobial susceptibility of these iso‐lates was detected by using K‐B test .All the strains were gene typed by using the pulsed field gel electrophoresis .Results The re‐sults of antimicrobial susceptibility test shown that the 61 isolates of Ab had high resistance rate ,and were multi‐drug resistant to common antibacterial agents ,except for tigecycline (the resistante rate was 11 .5% ) and minocycline (the resistante rate was 48 .0% ) .The 61 isolates of Ab were divided into 8 kinds of genotypes ,among which type A was the most prevalent one (25 strains) .Other genotypes were type B(10 strains) ,type C(6 strains) ,type D(4 strains) ,type E(8 strains) ,type F(3 strains) ,type G(4 strains) and type H(1 strain) .The isolates of Ab were with high homology .Conclusion Multi‐drug resistance is observed in strains of Ab isolates from patients with explosive injury .Clonal strains of AB may be disseminates among regions ,which indicates that high attention should be paid to these strains .
