Effect of compound fetal bovine liver extract combined with anti-viral effects on liver fibrosis in patients with cirrhosis treatment
- VernacularTitle:复方牛胎肝提取物联合抗病毒治疗对肝硬化患者肝纤维化指标的影响分析
- Author:
Mudan WANG
;
Haijun CAO
;
Shangao LI
;
Ling ZHU
;
Jianhao ZHENG
- Publication Type:Journal Article
- Keywords:
compound fetal bovine liver extract;
antiretroviral therapy;
cirrhosis;
liver fibrosis
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;(11):147-148,151
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of compound fetal liver extract combined with antiviral therapy on liver fibrosis in patients with cirrhosis.Methods 60 patients with liver cirrhosis from April 2014 to July 2015 were randomly divided into treatment group and control group(n=30).The patients in control group were treated with conventional anti viral therapy , 30 cases in treatment group were treated with compound fetal liver extract combined with antiviral therapy postoperative.Results 1 month after treatment, the treatment group serum liver fibrosis HA, PCM value respectively(107.5 ±17.8,99.8 ±14.9)ng/mL, were lower than in the control group (138.4 ±15.2,124.1 ±18.1)ng/mL(P<0.05).1 month after treatment, the treatment group liver fibrosis collagen type IV, III procollagen value respectively(58.9 ±11.0,109.2 ±11.1)μg/L, were lower than in the control group (85.7 ±11.2,122.7 ±11.3)μg/L(P<0.05).Conclusion Compound fetal bovine liver extract combined with anti-viral therapy in patients with cirrhosis has good, better than the use of antiviral drugs alone.
