Diffusion tensor imaging for evaluating white matter fiber tracts in patients with mild traumatic brain injury
10.3969/j.issn.1002-1671.2016.03.003
- VernacularTitle:轻型创伤性脑损伤脑白质纤维束扩散张量成像研究
- Author:
Lili HOU
;
Feng HAN
;
Deren WANG
;
Zheng PAN
- Publication Type:Journal Article
- Keywords:
mild traumatic brain injury;
diffusion tensor imaging;
apparent diffusion coefficient;
fractional anisotropy
- From:
Journal of Practical Radiology
2016;32(3):339-342,349
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the changes of white matter fiber tracts in mild traumatic brain injury(mTBI)patients by using DTI technique on 3.0T MR system,and evaluate the clinical diagnostic value of DTI.Methods Thirty mTBI and 30 matched health-y controls underwent conventional CT,MRI and DTI examinations.FA values and ADC values in the genu of the corpus callosum, the splenium of the corpus callosum,bilateral internal capsule,the cingulum bundle,the bilateral superior longitudinal fasciculus and the inferior longitudinal fasciculus of mTBI were measured in mTBI patients and controls at acute phase,subacute phase,5 weeks and 3 months post-trauma.The temporal changes of MRI data were observed.Results The FA values in the part of the white mat-ter fiber tracts reduced in the acute and subacute phase in mTBI patients (all P <0.05)in relative to controls (all P <0.05),At 5 weeks and 3 months post-trauma,the FA values also slightly lower in patients than controls.As for the genu of the corpus callosum and the splenium of the corpus callosum,the FA values in mTBI patients increased slightly at the acute stage (all P >0.05),but de-creased at 5 weeks-3 months post-trauma phase,though there was no significantly difference(all P >0.05).ADC values significantly decreased in the acute and subacute phase in mTBI patients,while they recovered thereafter (all P >0.05).Conclusion The sensi-tivity of DTI in detecting the lesions of mild traumatic brain damage is high,and it can display the damage of white matter.DTI could play an important role in the diagnosis of mTBI.
