Determination of heavy metals Pb,Cd,Sb in tetracaine hydrochloride injection by atomic absorption spectrometry-graphite furnace
- VernacularTitle:原子吸收－石墨炉法测定盐酸丁卡因注射液中重金属元素Pb，Cd，Sb的方法学研究
- Author:
Yinglin CHEN
;
Jianyou DUAN
;
Zhulian MEI
- Publication Type:Journal Article
- Keywords:
atomic absorption spectrometry-graphite furnace;
tetracaine hydrochloride injection;
heavy metal
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;(12):171-173,176
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish an external calibration method of atomic absorption spectrometry-graphite furnace for determination of heavy metals Pb,Cd,Sb in tetracaine hydrochloride injection.Methods Microwave digestion for the pretreatment method was used,three kinds of heavy metal elements were determined by graphite atomic absorption spectrometry-graphite furnace Results The linear ranges of Pb,Cd,Sb were 0-80.0 ng/mL,0-2.0 ng/mL,0-40.0 ng/mL,therecovies were 92.7%-105.7%,95.8%-103.4%,92.1%-103.5%,respetively.The relative standard deviationless than 6.0%(n=9).Conclusion The method is simple and accurate,which can be used for the control of Pb,Cd,Sb in tetracaine hydrochloride injection.
