Short-term clinical effect of Zhenwu decoction combined with taxol and carboplatin (TC) in treatment of post-operative patients with ovarian cancer
- VernacularTitle:真武汤联合紫衫醇＋卡铂（TC）方案治疗卵巢癌术后患者的近期临床效果
- Author:
Shouzhong WANG
;
Zhian GAO
- Publication Type:Journal Article
- Keywords:
Zhenwu decoction;
taxol and carboplatin ( TC);
ovarian cancer;
post-operative;
effect
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;(12):92-93,96
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe and analyze the short-term clinical effect of Zhenwu decoction combined with taxol and carboplatin (TC) in treatment of post-operative patients with ovarian cancer.Methods The clinical data of eighty-six post-operative patients with ovarian cancer from June 2014 to June 2015 in our hospital were retrospective analyzed, and randomly divided into control group and treatment group, 43 cases in each group.The control group received TC treatment and treatment group received Zhenwu decoction on the basis of control group with two courses, 21d of one course. The clinical effect were compared between two groups post-treatment.Results After treatment, the total efficacy in treatment group was higher than that in control group (88.37%vs.65.11%;χ2 =6.515,P<0.05), the improvement rate of life quality was higher (72.09% vs.27.91%;χ2 =16.790,P<0.05), the stable rate of life quality had no statistical difference (23.26%vs.30.23%;χ2 =0.534,P>0.05), the reducing rate of life quality was lower (4.65%vs.41.86%;χ2 =10.030,P<0.05), the effect of Karnofsky performance score (KPS) was higher (93.02% vs.72.09%;χ2 =6.541, P<0.05), the complication rate was lower (4.65% vs.18.60%;χ2 =4.074,P <0.05).Conclusion The clinical effect of Zhenwu decoction combined with taxol and carboplatin (TC) in treatment of post-operative patients with ovarian cancer was satisfying, which could improve prognosis and improve survival rate.
