Impact of laparoscopic surgery on incidence of deep venous thrombosis in lower limbs in patients undergoing hysterectomy
10.3969/j.issn.1671-8348.2015.35.021
- VernacularTitle:妇科腹腔镜手术对子宫切除术患者术后下肢深静脉血栓的影响
- Author:
Na ZHAO
;
Youchang LI
;
Bo CHENG
;
Chaowen LIU
- Publication Type:Journal Article
- Keywords:
laparoscopic;
hysterectomy;
venous thrombosis;
cell coagulation
- From:
Chongqing Medicine
2015;(35):4965-4967,4971
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the impact of laparoscopic surgery and that of open surgery on the coagulation function and incidence of deep venous thrombosis(DVT) in lower limbs in patients undergoing hysterectomy .Methods From April 2014 to A‐pril 2015 ,110 eligible patients were recruited .There was 57 patients received laparoscopic surgery ,and 53 patients received open surgery for hysterectomy .All patients underwent surgery under the general anesthesia .The APTT ,PT ,FIB ,and D‐dimer was de‐tected at 5 time points:before surgery ,surgery completion ,24 h after surgery ,48 h after surgery ,and 72 h after surgery .All patients were scheduled to ultrasound exam in lower limbs to detect the DVT at 24 ,48 and 72 h after surgery .Results Both groups showed decreased PT at surgery completion as compared with other time points (P<0 .05) ,decreased APTT at surgery completion and 24 h after surgery as compared with other time points(P<0 .05) ,and increased FIB at surgery completion and 24 h after surgery as compared with other time points(P<0 .05) .No significant difference was found in APTT ,PT ,and FIB at each time points between two groups(P>0 .05) .Both groups showed increased D‐dimer after surgery compared with that before surgery ;the laparoscopic group showed higher D‐dimer at 24 h after surgery ,and lower D‐dimer at 48 h after surgery than open group(P<0 .05) .The inci‐dence of DVT in laparoscopic group and open group was 14 .04(8/57) and 5 .66% (3/53) ,respectively ,with no significant difference between two groups(P>0 .05) .Conclusion Both the laparoscopic surgery and open surgery will activate the coagulation system , and lead to DVT ;as compared with open surgery ,the laparoscopic surgery could not reduce the incidence of DVT in lower limbs in patients undergoing hysterectomy .
