Isolation and antimicrobial resistance of Mycoplasma from urogenital tract
10.3969/j.issn.1671-9638.2015.12.008
- VernacularTitle:泌尿生殖道分离支原体及其耐药性
- Author:
Suling LIU
;
Tieying HOU
- Publication Type:Journal Article
- Keywords:
urogenital system;
infection;
Mycoplasma;
drug resistance,microbial
- From:
Chinese Journal of Infection Control
2015;(12):821-823,833
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the isolation and antimicrobial susceptibility of Mycoplasma from urogenital tract,and provide the basis for rational clinical treatment.Methods Urogenital tract specimens from 57 904 outpa-tients in a hospital between 2008 and 2014 were performedUreaplasma urealyticum (Uu)and Mycoplasma hominis (Mh)culture,identification,and antimicrobial susceptibility testing.Results Of 57 904 patients with urogenital in-fection,21 614 (37.33%)had positive culture for Mycoplasma,isolation rate of Mycoplasma in female and male were 42.14% (18 917/44 889)and 20.72% (2 697/13 015 )respectively;Mycoplasma was mainly isolated from population of 21 -40 years old;Uu≥104 CFU/mL and Mh<104 CFU/mL mixed infection was common(69.35%). The resistance of Mycoplasma to doxycycline,josamycin,and tetracycline were all low(<10%);resistance rates of Mh to doxycycline,erythromycin,clarithromycin,and roxithromycin were all significantly higher than Uu (all P <0.05).Conclusion Mycoplasma infection/carriage rate in female outpatients is significantly higher than male outpa-tients,antimicrobial profile of Uu is different from Mh,josamycin and doxycycline can be as the first choice for treatment of non-gonococcal urethritis (cervicitis)caused by Mycoplasma.
