Characterization and modulation of immunosuppression phase of sepsis
10.7644/j.issn.1674-9960.2015.12.018
- VernacularTitle:脓毒症免疫抑制的发生及其可能调节机制
- Author:
Jianli ZHAO
;
Fen AI
- Publication Type:Journal Article
- Keywords:
sepsis;
SIRS;
immunosuppression;
multiple organ failure;
T-lymphocytes
- From:
Military Medical Sciences
2015;39(12):956-959,969
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis,a complex clinical syndrome resulting from a harmful and damaging host response to infection, is the leading cause of mortality in intensive care units.Early diagnosis and appropriate intervention can improve the prognosis of patients with sepsis.Many studies have confirmed that sepsis at different stages is in different immune status.Priority used to be given to systemic inflammatory response, but immune-suppression has become the focus of study. Immune-suppression and secondary infection are the major causes of death of patients with sepsis.Study of sepsis is shifting to immune-suppression and its regulation mechanisms.
