Clinical application of platelet aggregation for white blood cell count
10.3969/j.issn.1673-4130.2016.06.012
- VernacularTitle:血小板聚集影响因素在血细胞计数中的临床应用
- Author:
Enliang HU
;
Yuan ZHAO
;
Yan WANG
;
Ailin FAN
;
Shanluan ZHENG
- Publication Type:Journal Article
- Keywords:
platelet aggregation;
anticoagulants;
pseudothrombocytopenia;
ethylenediamineteraacetic acid dipotassium-salt;
thylenediaminetetraacetic acid dependent pseudothrombocytopenia
- From:
International Journal of Laboratory Medicine
2016;37(6):749-750,753
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the cause of platelet aggregation in blood specimens ,so as to provide basis for reducing platelet aggregation ,and avoiding false positive of platelet count ,false report ,misdiagnosis and mistreatment .Methods The blood speci-mens which platelet was below 80 × 109 /L ,below 125 × 109 /L with histogram hinted platelet aggregation ,were smeared ,stained with Wright-Giemsa ,and observed by microscope for platelet morphological changes .The data between each groups were calculated and analyzed by statistical software SPSS version 18 .0 .Results A total of 184 cases of ethylenediaminetetraacetic acid dependent pseudothrombocytopenia(EDTA-PTCP) were found ,accounted for 0 .444 ‰ totally ,including 0 .244 ‰ of out-patients (101 cases) , 0 .159 ‰ of hospitalized patients (66 cases) ,and 0 .041 ‰ of health examination personnel (17 cases) .3 cases of multi-dependent pseudothrombocytopenia and 25 cases of pseudo platelet aggregation were found ,and accounted for 0 .007 ‰ and 0 .060 ‰ respec-tively .Conclusion The discovery of platelet aggregation which caused mainly by EDTA-PTCP ,still relies on microscopy ,and pseu-do platelet aggregation comes mainly from sampling ,so it needs to strengthen the skills training .