Progress in the application of infliximab in Kawasaki disease
10.3760/cma.j.issn.1673-4408.2015.06.018
- VernacularTitle:英夫利昔单抗治疗川崎病的应用进展
- Author:
Yaping LIU
- Publication Type:Journal Article
- Keywords:
Kawasaki disease;
Infliximab;
IVIG non-responsiveness
- From:
International Journal of Pediatrics
2015;42(6):666-668,672
- CountryChina
- Language:Chinese
-
Abstract:
Kawasaki disease is an acute and self-limited systemic vasculitis.Coronary artery lesions are the most common complications.The principal treatment with intravenous immunoglobulin and high doses of oral aspirin has significantly decreased the morbidity of coronary artery lesions.However, increased cases of IVIG non-responsiveness and refractory Kawasaki disease in recent years make the treatment more difficult.The existing progress indicates that infliximab provides a new therapeutic option for Kawasaki disease, especially for IVIG non-responsiveness and refractory Kawasaki disease.This paper reviews recent studies associated with application of infliximab in Kawasaki disease.
