Cryoprecipitate for external use of anal fistula of postoperative wound repair affect clinical research
10.3760/cma.j.issn.1008-1372.2015.10.020
- VernacularTitle:血浆冷沉淀外用对肛瘘术后创面修复的影响研究
- Author:
Jie HU
;
Gengxun LIU
;
Xiaogong JIANG
;
Yongyun DONG
;
Jiawei HU
;
Hongjun ZHU
;
Xia ZHONG
- Publication Type:Journal Article
- Keywords:
Plasma;
Precipitation;
Rectal fistula/SU;
Surgical wound infection/TH
- From:
Journal of Chinese Physician
2015;17(10):1513-1515,1519
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the cryoprecipitate effect of local external treatment of anal fistula surgical wound repair.Methods A total of 95 cases of low simple anal fistula patients was chosen, and was divided into three groups according to random number table method.The cryoprecipitate group (n =32 cases) began with cryoprecipitate dressing (2 layer) even to fill in a wound, once per day.The Kangfuxin group (n =32 cases) used Kangfuxin solution.The exposed burn ointment (MEBO) group (n =31 cases) used MEBO to cover the wound.The healing time, postoperative wound healing rate, the granulation tissue growth, new epithelial coverage, and adverse reactions were observed.Results The cryoprecipitate group in 14 d and 21 d had postoperative wound healing rate (60.97 ±4.20)％ and (97.69 ± 1.79)％ ,wound healing time (21.31 ±2.08)days;it had higher healing rate and shorter healing times compared to other two groups (P ＜0.05).Wound repaired more neatly;and 14d and 21d after the operation, wound granulation tissue growth rate [(61.06 ± 13.29) ％ and (97.63 ± 2.81) ％] and new epithelial coverage [(33.03 ±4.15)％ and (94.97 ±4.36)％] were more than the control groups (P ＜0.05) with less adverse reactions relative to control groups.Conclusions The cryoprecipitate contained in the composition has a strong biological activity.It can promote the wound tissue cell growth, and promote the wound repair.
