MicroRNAs as a Potential Marker in the Progress of Colorectal Cancer
10.3969/j.issn.1671-7414.2015.04.031
- VernacularTitle:MicroRNAs 作为结直肠癌潜在标记物的研究进展
- Author:
Qinjun WANG
;
Hongchun ZHANG
;
Xianjuan SHEN
;
Shaoqing JU
- Publication Type:Journal Article
- Keywords:
micro RNAs;
colorectal cancer;
biological markers;
target
- From:
Journal of Modern Laboratory Medicine
2015;(4):107-110,114
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs (miRNAs)are small,non-coding RNAs that regulate the translation of specific protein coding genes. Recent studies have revealed the role of miRNAs in a variety of basic biological and pathological processes.Previous studies have suggested miRNAs can be servered as a new tumor biomarker in the early diagnosis,treatment and assessment of prog-nosis of CRC,which also can be servered as the treatment target in vivo of CRC patients.This paper reviews the expression and targets of miRNAs,its mechanism of the development and prospect in clinical application in CRC.
