The correlation among acute cerebral infarction area,serum high sensitivity C reactive protein and homocysteine concentrations
10.3969/j.issn.1673-4130.2015.17.015
- VernacularTitle:急性脑梗死面积与患者血清超敏C反应蛋白、同型半胱氨酸水平的相关性分析
- Author:
Guiqin RUAN
;
Ying LV
;
Qingling HUANG
- Publication Type:Journal Article
- Keywords:
cerebral infarction;
high sensitivity C reactive protein;
homocysteine
- From:
International Journal of Laboratory Medicine
2015;(17):2490-2491,2494
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the correlation among acute cerebral infarction area ,serum high sensitivity C reactive protein(hs‐CRP)andhomocysteine(Hcy)concentrations.Methods 112acutecerebralinfarctionpatientsreceivedinneurologicaldepartment of the hospital were enrolled in the study .They were divided into small infarction size group(n=56) and large infarction size group (n=56) ,according to the cerebral infarction area determined by using MRI and MRA .Common information of patients such as age , sex ,smoking ,drinking ,hypertension ,hyperlipidemia and diabetes history were recorded ,serum hs‐CRP and Hcy concentrations were also determined .The comparison between the 2 groups were performed on those common information and test results .Results There was no statistically significant difference on age ,alcohol consumption ,smoking ,hypertension and high cholesterol between the two groups(P>0 .05) .Serum concentrations of hs‐CRP ,Hcy and blood glucose in small infarction size group were lower than those in large infarction size group(P<0 .05) ,and the infarct areas were positively correlated with hs‐CRP ,Hcy and blood glucose levels(r=0 .625 ,0 .833 ,0 .651 ,P<0 .05) .Conclusion Serum hs‐CRP ,Hcy level are high risk factor for atherosclerosis plaque for‐mation of acute cerebral infarction patients ,the serum levels help predict the infarction area ,and diabetes is an important cause of cerebral infarction .
