Progress in preparation of cerebral ischemia reperfusion injury in animal models
- VernacularTitle:制备脑缺血再灌注损伤动物模型的研究进展
- Author:
Lu CHEN
;
Weiwei LI
;
Chunhui LIU
- Publication Type:Journal Article
- Keywords:
cerebral ischemia reperfusion injury;
animal models;
preparation
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;35(10):158-160,167
- CountryChina
- Language:Chinese
-
Abstract:
Ischemic cerebrovascular disease(ICVD) is temporary or permanent reduction of blood flow of the main arteries of the brain caused by cerebral transient,sudden,reversible neurological dysfunction.Timely recovery of blood supply to the brain is the most important way to save the patient's life,but at the same time gave restore blood perfusion brain tissue organs brought new damage,which is cerebeal ischemia reperfusion injury(CIRI).How to build an ideal,efficient,easy to operate brain ischemia-reperfusion injury in animal models to simulate the clinical study,and how to improve and innovate this model by researchers in recent years were reviewed in this article.
