Effect of rivaroxaban compared with Xuesaitong injection on deep venous thrombosis of lower extremity after spinal surgery
- VernacularTitle:利伐沙班与血塞通注射液联合应用对脊柱术后下肢深静脉血栓的作用
- Author:
Bing BAI
;
Baocheng JIN
;
Dawei LIU
- Publication Type:Journal Article
- Keywords:
rivaroxaban;
Xuesaitong injection;
after spinal surgery;
deep venous thrombosis
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;35(10):88-89,92
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of the combination of rivaroxaban and Xuesaitong injection on deep venous thrombosis (DVT) of lower extremity after spinal surgery.Methods The clinical data of 90 patients undergoing spinal surgery from May 2013 to May 2015 were retrospective analyzed.The patients were divided into two groups randomly: the treatment group and control group.Forty-five patients in treatment group were treated with rivaroxaban and Xueshuantong injection from 1 st day after surgery to one week after off-bed activity, and forty-five patients in control group were treated with rivaroxaban alone.The vessels of lower extremity were detected by doppler ultrasonography pre-surgery, 7-10d and 3 months post-surgery, then the rates of DVT and pulmonary embolism were statistically analysed.Results The DVT rate in treatment group was 8.89%(4 cases), which was significantly lower than 24.4% (11 cases) in control group (P<0.05).Conclusion The anticogulant effect of the combination of rivaroxaban and Xuesaitong injection is stronger than rivaroxaban alone.
