The Significance of fibrin monomer,D-Dimer and other blood coagulation indicators detection in the early diagnosis of DIC in obstetrics
10.3969/j.issn.1673-4130.2015.20.030
- VernacularTitle:纤维蛋白单体、D-二聚体等凝血指标检测对产科早期D IC诊断的意义
- Author:
Heping PENG
;
Donglian CHEN
;
Xiaoying CHEN
;
Qingying ZHANG
;
Baorong DONG
;
Fanpeng ZENG
- Publication Type:Journal Article
- Keywords:
fibrin monomer;
D-dimer;
disseminated intravascular coagulation;
pregnant women
- From:
International Journal of Laboratory Medicine
2015;(20):2992-2993,2996
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the significance of fibrin monomer(FM ) ,D‐Dimer(D‐D) and other blood coagulation indica‐tors detection in the early diagnosis of disseminated intravascular coagulation(DIC) in obstetrics .Methods 90 healthy women with‐out pregnancy(control group) ,270 normal pregnant women including early ,mid‐,late pregnancy(90 cases for each) ,36 early DIC puerperas(early DIC group) were enrolled in the study .FM ,D‐D ,prothrombin time (PT ) ,activated partial coagulation activity (APTT) ,fibrinogen(FIB) levels were detected for those people .Results The levels of D‐D and FM in early DIC group were signif‐icantly higher than those in control group (P<0 .05) ,and PT ,APTT in late pregnant group were significantly shorter than those in early ,mid‐pregnant group and control group ,while FIB was significantly higher ,the difference was statistically significant(P<0 .05) .Conclusion PT ,APTT and FIB can reflect the high blood coagulation state in the late pregnancy ,but can not be used in the diagnosis of early DIC .D‐D and FM have important value for the early diagnosis of DIC in obstetrics .
