The significance of blood serum Hcys,folic acid,vitamin B12 detection in mid and late pregnancy for the the patients with pregnancy-induced hypertension syndrome
10.3969/j.issn.1673-4130.2015.20.033
- VernacularTitle:妊娠中晚期血清同型半胱氨酸、叶酸、维生素B 12水平检测对妊高征患者意义
- Author:
Xiangling CHEN
- Publication Type:Journal Article
- Keywords:
pregnancy-induced hypertension syndrome;
homocysteine;
folic acid;
vitamin B12
- From:
International Journal of Laboratory Medicine
2015;(20):3000-3001,3004
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the significance of homocysteine(Hcy) ,folic acid ,vitamin B12 detection in mid and late pregnancy for the the patients with pregnancy‐induced hypertension syndrome .Methods 76 women who gave birth in the hospital from Janu‐ary 2012 to December 2013 were enrolled in the study .38 of them were patients with pregnancy‐induced hypertension syndrome (pregnancy‐induced hypertension group) ,the other 38 were healthy pregnant women(normal pregnancy group) .Fasting venous blood of those pregnant women were collected and tested for Hcy ,folic acid ,and vitamin B12 concentrations by using fluorescence polarization immunoassay ,ion serum folate levels capture immunoassay and microparticle enzyme‐linked immunosorbent assay re‐spectively .Then the test results were compared between the two groups .Results The serum concentrations of Hcy in pregnancy‐induced hypertension group were higher than that in normal pregnancy group ,and the difference was pregnancy‐induced hyperten‐sion gourp statistically significant(P<0 .05) .The serum concentrations of folic acid in pregnancy‐induced hypertension gourp were lower than that in normal pregnancy group ,and the difference was statistically significant(P<0 .05) .The comparision of serum vi‐tamin B12 concentrations between the two groups showed no statistically significant difference(P>0 .05) .Conclusion The detection of serum Hcy and folic acid could help to guide the treatment of patients with pregnancy induced hypertension syndrome .
