Correlation between antiphospholipid antibody syndrome and the early onset of preeclampsia
10.3969/j.issn.1006-5725.2015.20.007
- VernacularTitle:抗磷脂抗体综合征与早发型子痫前期的相关性
- Author:
Xianxia CHEN
;
Zhixia TANG
;
Xianglian MENG
;
Ge DONG
;
Junqiang ZHANG
;
Xiaoyu CHEN
- Publication Type:Journal Article
- Keywords:
Early onset of preeclampsia;
Antiphospholipid antibody syndrome;
Correlation
- From:
The Journal of Practical Medicine
2015;(20):3308-3310,3311
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between antiphospholipid antibody syndrome and the early onset of preeclampsia. Methods From May 2010 to July 2013, one hundred and threecases in-patient treatment of the early onset preeclampsia were enrolled in this study. The maternal serum anticardiolipin antibodies(ACA)and anti-β2-glycoproteinⅠantibody (Aβ2-GPⅠ) were detected by ELISA method. 58 cases of pregnant women were randomly divided into the routine treatment group (30 cases) and the anticoagulant therapy group (28 cases). Results ACA positive predictive value of the early onset preeclampsia value was 3.9%. No significant difference was found in the prolonged anticoagulation of early onset preeclampsia time between the control group and the treatment group. Conclusion ACA may not be used to predict the early onset preeclampsia. Anticoagulation therapy can′t extend the early onset preeclampsia time and improve the outcome of pregnancy.